No'mo stands for not homosexual or the recently popular, "no homo."
1. You don't think an individual in question is gay.
2. You made a comment that could be taken homosexually, and want to nullify it.
1. Oh, Nick is too much of a slob, he's definitely no'mo.
2. Guy1: "Hot dogs are my favorite!"
Guy2: "Dude, really?"
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