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1.
when a shit resembles a foot-long subway, often these types of shits span over a few days, hence why "shits" is plural.

they often result in the perpetrator spending an unusually long amount of time in the bathroom.

they can also be extremely painful on some occasions
Greg: "hey man you were in there for ages, you ok?"

Mike: " nahh I've got the Subway Shits"

Greg: "ah sounds painful"
por joshtommo93 11 de Setembro de 2011
 
2.
Its when you contract diarrhea after you have eaten day old subway.
Andrew:Why does your uncle keep pulling over to use the restroom?

Eric: Its cuz he has the Subway shits

Andrew: Really he tried making me eat that shit, hes gonna have that throughout the trip
por Ch0c0late M00se 29 de Julho de 2011